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Kais Mnafgui Selected Research

Isoproterenol (Isoprenaline)

11/2022In vivo evaluation and molecular docking studies of Schinus molle L. fruit extract protective effect against isoproterenol-induced infarction in rats.
1/2022A novel synthetised sulphonylhydrazone coumarin (E)-4-methyl-N'-(1-(3-oxo-3H-benzo[f]chromen-2- yl)ethylidene)benzenesulphonohydrazide protect against isoproterenol-induced myocardial infarction in rats by attenuating oxidative damage, biological changes and electrocardiogram.
12/2021Anti-embolic and anti-oxidative effects of a novel (E)-4-amino-N'-(1-(7-hydroxy-2-oxo-2H-chromen-3-yl) ethylidene) benzohydrazide against isoproterenol and vitamin-K induced ischemic stroke.
6/2021Cardiopreventive capacity of a novel (E)-N'-(1-(7-methoxy-2-oxo-2H-chromen-3-yl) ethylidene)-4-methylbenzenesulfonohydrazide against isoproterenol-induced myocardial infarction by moderating biochemical, oxidative stress, and histological parameters.
8/2020(E)-N'-(1-(3-oxo-3H-benzo[f]chromen-2-yl)ethylidene)benzohydrazide protecting rat heart tissues from isoproterenol toxicity: Evidence from in vitro and in vivo tests.
1/2020(E)-N'-(1-(7-Hydroxy-2-Oxo-2H-Chromen-3-Yl) Ethylidene) Benzohydrazide, a Novel Synthesized Coumarin, Ameliorates Isoproterenol-Induced Myocardial Infarction in Rats through Attenuating Oxidative Stress, Inflammation, and Apoptosis.
10/2019Cardioprotective effects of (E)-4-hydroxy-N'-(1-(3-oxo-3H-benzo[f]chromen-2-yl)ethylidene)benzohydrazide: a newly synthesized coumarin hydrazone against isoproterenol-induced myocardial infarction in a rat model.
10/2017Cardiopreventive effect of ethanolic extract of Date Palm Pollen against isoproterenol induced myocardial infarction in rats through the inhibition of the angiotensin-converting enzyme.
10/2016Anti-inflammatory, Antithrombotic and Cardiac Remodeling Preventive Effects of Eugenol in Isoproterenol-Induced Myocardial Infarction in Wistar Rat.
4/2016Protective Effect of Hydroxytyrosol Against Cardiac Remodeling After Isoproterenol-Induced Myocardial Infarction in Rat.
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Kais Mnafgui Research Topics

Disease

12Myocardial Infarction
11/2022 - 11/2013
7Body Weight (Weight, Body)
01/2022 - 01/2012
6Necrosis
01/2022 - 10/2016
4Hypertension (High Blood Pressure)
08/2016 - 12/2011
3Cardiomegaly (Heart Hypertrophy)
12/2021 - 08/2020
3Inflammation (Inflammations)
10/2021 - 03/2014
2Infarction (Infarctions)
11/2022 - 08/2021
2Ischemic Stroke
12/2021 - 08/2021
2Cardiotoxicity
10/2021 - 02/2020
2Ventricular Remodeling
10/2017 - 10/2016
1Atrial Flutter (Flutter, Atrial)
12/2021
1Stroke (Strokes)
12/2021
1Fibrosis (Cirrhosis)
10/2021
1Hyponatremia
08/2021
1Brain Ischemia (Cerebral Ischemia)
08/2021
1Brain Edema (Cerebral Edema)
08/2021
1Thrombosis (Thrombus)
08/2020
1Edema (Dropsy)
01/2020
1Heart Injuries
01/2020
1Spasm (Spasms)
08/2016
1Diarrhea
08/2016
1Obesity
07/2015
1Hyperlipidemias (Hyperlipidemia)
01/2013
1Hyperglycemia
01/2013

Drug/Important Bio-Agent (IBA)

12Isoproterenol (Isoprenaline)FDA LinkGeneric
11/2022 - 01/2015
9EnzymesIBA
08/2021 - 12/2011
6Biomarkers (Surrogate Marker)IBA
01/2022 - 03/2014
6Troponin T (Troponin T1)IBA
12/2021 - 06/2015
5coumarinIBA
01/2022 - 10/2019
5Fibrinogen (Factor I)FDA Link
01/2022 - 01/2020
5Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
08/2021 - 01/2015
5LipidsIBA
01/2020 - 03/2014
3AcenocoumarolIBA
12/2021 - 01/2020
3Glutathione PeroxidaseIBA
08/2021 - 10/2016
3Lipase (Acid Lipase)FDA Link
08/2016 - 01/2012
2Clopidogrel (Plavix)FDA Link
01/2022 - 10/2016
2Biological ProductsIBA
01/2022 - 07/2015
2Pharmaceutical PreparationsIBA
01/2022 - 10/2019
2Superoxide DismutaseIBA
08/2021 - 10/2016
2Thiobarbituric Acid Reactive SubstancesIBA
08/2021 - 10/2016
2oleuropeinIBA
08/2021 - 01/2015
2oxidized low density lipoproteinIBA
01/2020 - 01/2012
2L-Lactate Dehydrogenase (Lactate Dehydrogenase)IBA
10/2019 - 06/2015
2Aspartate Aminotransferases (Aspartate Transaminase)IBA
10/2019 - 06/2015
2Alanine Transaminase (SGPT)IBA
10/2019 - 06/2015
2MB Form Creatine KinaseIBA
10/2019 - 06/2015
2EugenolIBA
10/2016 - 12/2013
2AlloxanIBA
08/2016 - 12/2013
2Volatile Oils (Essential Oils)IBA
08/2016 - 12/2011
2CarbohydratesIBA
03/2014 - 12/2011
1Vitamin KFDA Link
12/2021
1Caspase 3 (Caspase-3)IBA
10/2021
1Permethrin (Ambush)FDA LinkGeneric
10/2021
1Neuroprotective AgentsIBA
08/2021
1CatalaseIBA
08/2021
1Lactic Acid (Lactate)FDA LinkGeneric
08/2021
1Creatine Kinase (Creatine Phosphokinase)IBA
08/2021
1Superoxides (Superoxide)IBA
06/2021
1AntioxidantsIBA
06/2021
1HDL LipoproteinsIBA
06/2021
1AnticoagulantsIBA
08/2020
1cypermethrin (alphamethrin)IBA
02/2020
1(E)- N'- (1- (7- hydroxy- 2- oxo- 2H- chromen- 3- yl) ethylidene) benzohydrazideIBA
01/2020
1trans-crotonin (CTN)IBA
01/2020
1HydrazonesIBA
10/2019
1Reactive Oxygen Species (Oxygen Radicals)IBA
10/2017
1Proteins (Proteins, Gene)FDA Link
10/2016
13,4-dihydroxyphenylethanol (hydroxytyrosol)IBA
04/2016
1cinnamic acidIBA
07/2015
1Antihypertensive Agents (Antihypertensives)IBA
07/2015
1PhytochemicalsIBA
07/2015
1Linseed Oil (Flaxseed Oil)IBA
06/2015
1Alkaline PhosphataseIBA
06/2015
1Hypoglycemic Agents (Hypoglycemics)IBA
03/2014
1trigonellineIBA
01/2013
1LeptinIBA
01/2012
1FlavonoidsIBA
01/2012
1ElectrolytesIBA
01/2012

Therapy/Procedure

1Injections
11/2022
1Oral Administration
08/2020
1Traditional Medicine (Folk Remedies)
08/2016
1Subcutaneous Injections
01/2015